Dr. Barbara Saccà

Wissenschaftliche Mitarbeiterin
Zentrum für Medizinische Biotechnologie
Universität Duisburg-Essen

since 4/12
Independent research position at the University of Duisburg-Essen

Principal Investigator at the Technische Universität Dortmund, Germany (funded by the Deutsche Forschungsgemeinschaft, grant SA 1952/1-1)

2006 – 2009
Postdoc with C.M. Niemeyer, TU Dortmund

2004 – 2005
Postdoc with A. Bensimon, Institut Pasteur, Paris, France

2003 – 2004
Postdoc with J.L. Mergny, MNHN, Paris, France

PhD Chemistry, MPI of Biochemistry, Martinsried

I work in the field of self-assembled DNA nanostructures. By means of computer programs it is possible to design 100 nm-sized supramolecular DNA structures of any desired shape. Such structures (also called DNA origami) are molecularly addressable in a 3D space with a precision of few nanometers. I am interested in the multivalent chemical modification of such nanoscaled objects for applications in nanomedicine and materials science.

Weitere Interessen:
• (Bio)physical characterization of (modified) DNA-origami by single-molecules techniques
• Modification of DNA-origami with nanoparticles for generation of new materials with peculiar electromagnetic properties
• Development of softwares for assisting in the design of chemically modified DNA origami